PUBLICATIONS 

2020

43. Fang Z, Chen S, Manchanda Y, Bitsi S, Pickford P, David A, Shchepinova MM, Corrêa IR Jr, Hodson DJ, Broichhagen J, Tate EW, Reimann F, Salem V, Rutter GA, Tan T, Bloom SR, Tomas A, Jones B. Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells. Int J Mol Sci. 2020 Nov 9;21(21):8404. doi: 10.3390/ijms21218404. PMID: 33182425; PMCID: PMC7664906.

42. Carrat GR, Haythorne E, Tomas A, Haataja L, Müller A, Arvan P, Piunti A, Cheng K, Huang M, Pullen TJ, Georgiadou E, Stylianides T, Amirruddin NS, Salem V, Distaso W, Cakebread A, Heesom KJ, Lewis PA, Hodson DJ, Briant LJ, Fung ACH, Sessions RB, Alpy F, Kong APS, Benke PI, Torta F, Teo AKK, Leclerc I, Solimena M, Wigley DB, Rutter GA. The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis. Mol Metab. 2020 Oct;40:101015. doi: 10.1016/j.molmet.2020.101015. Epub 2020 May 13. PubMed PMID: 32416313; PubMed Central PMCID: PMC7322359.

41. Pickford P, Lucey M, Fang Z, Bitsi S, de la Serna JB, Broichhagen J, Hodson DJ, Minnion J, Rutter GA, Bloom SR, Tomas A, Jones B. Signalling, trafficking and glucoregulatory properties of glucagon-like peptide-1 receptor agonists exendin-4 and lixisenatide. Br J Pharmacol. 2020 Sep;177(17):3905-3923. doi: 10.1111/bph.15134. Epub 2020 Jun 19. PMID: 32436216; PMCID: PMC7429481.

40.Kemkem Y, Nasteska D, de Bray A, Bargi-Souza P, Peliciari-Garcia RA, Guillou A, Mollard P, Hodson DJ, Schaeffer M. Maternal hypothyroidism in mice influences glucose metabolism in adult offspring. Diabetologia. 2020 May 30;. doi: 10.1007/s00125-020-05172-x. [Epub ahead of print] PubMed PMID: 32472193.

39. Rutter GA, Ninov N, Salem V, Hodson DJ. Comment on Satin et al. "Take Me To Your Leader": An Electrophysiological Appraisal of the Role of Hub Cells in Pancreatic Islets. Diabetes 2020;69:830-836. Diabetes. 2020 Sep;69(9):e10-e11. doi: 10.2337/db20-0501. PubMed PMID: 32820056; PubMed Central PMCID: PMC7458040.

38. Poc P, Gutzeit VA, Ast J, Lee J, Jones BJ, D'Este E, Mathes B, Lehmann M, Hodson DJ, Levitz J, Broichhagen J. Interrogating surface versus intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates. Chem Sci. 2020 Jul 7;11(30):7871-7883. doi: 10.1039/d0sc02794d. PubMed PMID: 34123074; PubMed Central PMCID: PMC8163392.

 

37. Viloria K, Nasteska D, Briant LJB, Heising S, Larner DP, Fine NHF, Ashford FB, da Silva Xavier G, Ramos MJ, Hasib A, Cuozzo F, Manning Fox JE, MacDonald PE, Akerman I, Lavery GG, Flaxman C, Morgan NG, Richardson SJ, Hewison M, Hodson DJ. Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion. Cell Rep. 2020 Jun 16;31(11):107761. doi: 10.1016/j.celrep.2020.107761. PMID: 32553153; PMCID: PMC7302426.

36. Seabright AP, Fine NHF, Barlow JP, Lord SO, Musa I, Gray A, Bryant JA, Banzhaf M, Lavery GG, Hardie DG, Hodson DJ, Philp A, Lai YC. AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner. FASEB J. 2020 May;34(5):6284-6301. doi: 10.1096/fj.201903051R. Epub 2020 Mar 22. PubMed PMID: 32201986; PubMed Central PMCID: PMC7212019.

35. Hodson DJ, Rorsman P. A Variation on the Theme: SGLT2 Inhibition and Glucagon Secretion in Human Islets. Diabetes. 2020 May;69(5):864-866. doi: 10.2337/dbi19-0035. PubMed PMID: 32312904; PubMed Central PMCID: PMC7171971.

34. Sayers SR, Beavil RL, Fine NHF, Huang GC, Choudhary P, Pacholarz KJ, Barran PE, Butterworth S, Mills CE, Cruickshank JK, Silvestre MP, Poppitt SD, McGill AT, Lavery GG, Hodson DJ, Caton PW. Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes. Diabetologia. 2020 Feb;63(2):313-323. doi: 10.1007/s00125-019-05029-y. Epub 2019 Nov 15. PubMed PMID: 31732790; PubMed Central PMCID: PMC6946736.

 

33. Nasteska D, Hodson DJ. GPR119 Agonism Revisited: A Novel Target for Increasing β-Cell Mass? Endocrinology. 2020 Feb 1;161(2):bqz018. doi: 10.1210/endocr/bqz018. PMID: 32053720.

32. Ast J, Arvaniti A, Fine NHF, Nasteska D, Ashford FB, Stamataki Z, Koszegi Z, Bacon A, Jones BJ, Lucey MA, Sasaki S, Brierley DI, Hastoy B, Tomas A, D'Agostino G, Reimann F, Lynn FC, Reissaus CA, Linnemann AK, D'Este E, Calebiro D, Trapp S, Johnsson K, Podewin T, Broichhagen J, Hodson DJ. Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. Nat Commun. 2020 Jan 24;11(1):467. doi: 10.1038/s41467-020-14309-w. PMID: 31980626; PMCID: PMC6981144.