PUBLICATIONS

55. Ast J, Broichhagen J, Hodson DJ. Reagents and models for detecting endogenous GLP1R and GIPR. EBioMedicine. 2021 Dec;74:103739. doi: 10.1016/j.ebiom.2021.103739. Epub 2021 Dec 12. Review. PubMed PMID: 34911028; PubMed Central PMCID: PMC8669301.

54. Costa A, Ai M, Nunn N, Culotta I, Hunter J, Boudjadja MB, Valencia-Torres L, Aviello G, Hodson DJ, Snider BM, Coskun T, Emmerson PJ, Luckman SM, D'Agostino G. Anorectic and aversive effects of GLP-1 receptor agonism are mediated by brainstem cholecystokinin neurons, and modulated by GIP receptor activation. Mol Metab. 2021 Nov 26;55:101407. doi: 10.1016/j.molmet.2021.101407. [Epub ahead of print] PubMed PMID: 34844019; PubMed Central PMCID: PMC8689241.

 

53. Cartwright DM, Oakey LA, Fletcher RS, Doig CL, Heising S, Larner DP, Nasteska D, Berry CE, Heaselgrave SR, Ludwig C, Hodson DJ, Lavery GG, Garten A. Nicotinamide riboside has minimal impact on energy metabolism in mouse models of mild obesity. J Endocrinol. 2021 Sep 9;251(1):111-123. doi: 10.1530/JOE-21-0123. PubMed PMID: 34370682.

 

52. Pickford P, Lucey M, Rujan RM, McGlone ER, Bitsi S, Ashford FB, Corrêa IR, Hodson DJ, Tomas A, Deganutti G, Reynolds CA, Owen BM, Tan TM, Minnion J, Jones B, Bloom SR. Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist. Mol Metab. 2021 Sep;51:101242. doi: 10.1016/j.molmet.2021.101242. Epub 2021 Apr 30. PubMed PMID: 33933675; PubMed Central PMCID: PMC8163982.

 

51. Nasteska D, Cuozzo F, Viloria K, Johnson EM, Thakker A, Bany Bakar R, Westbrook RL, Barlow JP, Hoang M, Joseph JW, Lavery GG, Akerman I, Cantley J, Hodson L, Tennant DA, Hodson DJ. Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice. JCI Insight. 2021 Aug 23;6(16). doi: 10.1172/jci.insight.140288. PubMed PMID: 34264866; PubMed Central PMCID: PMC8409982.

 

50. Marzook A, Chen S, Pickford P, Lucey M, Wang Y, Corrêa IR Jr, Broichhagen J, Hodson DJ, Salem V, Rutter GA, Tan TM, Bloom SR, Tomas A, Jones B. Evaluation of efficacy- versus affinity-driven agonism with biased GLP-1R ligands P5 and exendin-F1. Biochem Pharmacol. 2021 Aug;190:114656. doi: 10.1016/j.bcp.2021.114656. Epub 2021 Jun 12. PubMed PMID: 34129856; PubMed Central PMCID: PMC8346945.

 

49. Lucey M, Ashik T, Marzook A, Wang Y, Goulding J, Oishi A, Broichhagen J, Hodson DJ, Minnion J, Elani Y, Jockers R, Briddon SJ, Bloom SR, Tomas A, Jones B. Acylation of the incretin peptide exendin-4 directly impacts GLP-1 receptor signalling and trafficking. Mol Pharmacol. 2021 Jul 27;. doi: 10.1124/molpharm.121.000270. [Epub ahead of print] PubMed PMID: 34315812.

 

48. Olaniru OE, Cheng J, Ast J, Arvaniti A, Atanes P, Huang GC, King AJF, Jones PM, Broichhagen J, Hodson DJ, Persaud SJ. SNAP-tag-enabled super-resolution imaging reveals constitutive and agonist-dependent trafficking of GPR56 in pancreatic β-cells. Mol Metab. 2021 Jul 2;53:101285. doi: 10.1016/j.molmet.2021.101285. [Epub ahead of print] PubMed PMID: 34224919; PubMed Central PMCID: PMC8326393.

47. Cadilhac C, Bachy I, Forget A, Hodson DJ, Jahannault-Talignani C, Furley AJ, Ayrault O, Mollard P, Sotelo C, Ango F. Excitatory granule neuron precursors orchestrate laminar localization and differentiation of cerebellar inhibitory interneuron subtypes. Cell Rep. 2021 Mar 30;34(13):108904. doi: 10.1016/j.celrep.2021.108904. PubMed PMID: 33789110.

46. McLean BA, Wong CK, Campbell JE, Hodson DJ, Trapp S, Drucker DJ. Revisiting the Complexity of GLP-1 Action from Sites of Synthesis to Receptor Activation. Endocr Rev. 2021 Mar 15;42(2):101-132. doi: 10.1210/endrev/bnaa032. PubMed PMID: 33320179; PubMed Central PMCID: PMC7958144.

45. Viloria K, Hewison M, Hodson DJ. Vitamin D binding protein/GC-globulin: a novel regulator of alpha cell function and glucagon secretion. J Physiol. 2021 Mar 15;. doi: 10.1113/JP280890. [Epub ahead of print] PubMed PMID: 33719063.

44. Nasteska D, Fine NHF, Ashford FB, Cuozzo F, Viloria K, Smith G, Dahir A, Dawson PWJ, Lai YC, Bastidas-Ponce A, Bakhti M, Rutter GA, Fiancette R, Nano R, Piemonti L, Lickert H, Zhou Q, Akerman I, Hodson DJ. PDX1LOW MAFALOW β-cells contribute to islet function and insulin release. Nat Commun. 2021 Jan 29;12(1):674. doi: 10.1038/s41467-020-20632-z. PMID: 33514698; PMCID: PMC7846747.

2021